Boot Failure: Macrium Reflect 6 USB neither Shows Hard Disk nor OS

Hi, recently my PC was working fine but suddenly i got boot problem like "a device is not connected" and later on "BCD boot file configuration not valid". After a lot of fuss, i downloaded Macrium Reflect USB with WinPE 10. I first used Rufus with NTFS file format to create the bootable Macrium Reflect USB but when booted, Marcium reflect neither found an operating system nor showing any hard disk in the computer, although hard disk is showing in the BIOS. Later on I googled and found that I should make a bootable USB using Fat32 file system since I have UEFI BIOS. So i did that using Rufus again and still Macrium Reflect shows nothing. I dont want to install windows again, but want to restore/fixboot to the previous working condition. Any help would be appreciated.

Thanks.

PC Configuration:
Intel Core i5 Skylake
Gigabyte H110 S2PH
Kingston 8GB Hyper X
1 TB SATA WD Black
Windows 10 Pro